Washington:
A new study has explored that active compound of chili peppers was found to have beneficial effects on liver damage.
The study conducted by European Association for the Study of the Liver found out that capsaicin was found to reduce the activation of hepatic stellate cells (HSCs) in mice models. HSCs are the major cell type involved in liver fibrosis, which is the formation of scar tissue in response to liver damage.
CCl4 is an inorganic compound that was widely used in fire extinguishers, as a precursor to refrigerants and as a cleaning agent. It is now known to be one of the most potent hepatotoxins.
The study demonstrates that capsaicin partially improved liver damage in the BDL mice and inhibited further progression of the injury and in the second group of CCl4-treated mice, capsaicin prevented livers from injury development but did not reduce the fibrosis when it was already established.
