The 38-year-old pacer had missed the last game against Kings XI Punjab where his team was bundeled out for 67 runs.
"Zaheer will be missing the match against Sunrisers Hyderabad due to the hamstring strain that he suffered during the match against Kolkata Knight Riders but he is unlikely to make a comeback," PTI quoted a team source as saying.
"He will have little time to recover from the strain due to the hectic schedule of IPL. Karun Nair will be the stand-in captain for tomorrow," he added.
Delhi are languishing at the eighth spot with only two wins in their eight games so far.
(With inputs from PTI)